HessianLogIC50: Compute the Hessian matrix of the sum-of-squares loss...

Description Usage Arguments Value

Description

Compute the Hessian matrix of the sum-of-squares loss function with reparameterization.

Usage

1
HessianLogIC50(retheta, x, y)

Arguments

retheta

Parameters of a 4PL model among which the EC50 parameter is in the log 10 dose scale

x

Doses

y

Response

Value

Hessian matrix of the sum-of-squares loss function in terms of reparameterized parameters.


ahwbest/drra documentation built on May 10, 2019, 7:35 a.m.