xCellAnalysis: The xCell analysis pipeline

Description Usage Arguments Value

Description

xCellAnalysis Returns the xCell cell types enrichment scores.

Usage

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xCellAnalysis(expr, signatures = NULL, genes = NULL, spill = NULL,
  rnaseq = TRUE, file.name = NULL, scale = TRUE, alpha = 0.5,
  save.raw = FALSE, parallel.sz = 4)

Arguments

expr

the gene expression data set. A matrix with row names as symbols and columns as samples.

signatures

a GMT object of signatures.

genes

list of genes to use in the analysis.

spill

the Spillover object for adjusting the scores.

rnaseq

if true than use RNAseq spillover and calibration paramters, else use array parameters.

file.name

string for the file name for saving the scores. Default is NULL.

scale

if TRUE, uses scaling to trnasform scores using fit.vals

alpha

a value to override the spillover alpha parameter. Deafult = 0.5

save.raw

TRUE to save a raw

parallel.sz

integer for the number of threads to use. Default is 4.

Value

the adjusted xCell scores


alex-pinto/xc documentation built on May 23, 2019, 6:02 p.m.