l1000_es: Effect size values for LINCS l1000 signatures.

Description Usage Format Details Value References

Description

Moderated unbiased effect sizes values for all 230829 LINCS l1000 signatures.

Usage

1

Format

An object of class matrix with 1001 rows and 230829 columns.

Details

Calculated as described by Marot et al (see reference) using toptable from limma and effectsize from metaMA.

Value

A matrix where columns correspond to perturbagens and rows to gene symbols.

References

Marot G, Foulley JL, Mayer CD, Jaffrézic F. Moderated effect size and P-value combinations for microarray meta-analyses. Bioinformatics. 2009 Oct 15;25(20):2692-9. doi: 10.1093/bioinformatics/btp444.


alexvpickering/ccdata documentation built on Oct. 2, 2020, 7:20 a.m.