Description Usage Arguments Details Value See Also Examples
Function extracts mu (overall mean effect size) and dprimes (unbiased effect sizes from each contrast).
1 | get_dprimes(es)
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es |
Result of call to |
Result used to query connectivity map drugs and predicted drug combinations.
List containing:
meta |
Named numeric vector with overall mean effect sizes for all genes from meta-analysis. |
contrasts |
List of named numeric vectors (one per contrast) with unbiased effect sizes for all measured genes. |
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 | library(crossmeta)
library(lydata)
data_dir <- system.file("extdata", package = "lydata")
# gather GSE names
gse_names <- c("GSE9601", "GSE15069", "GSE50841", "GSE34817", "GSE29689")
# load previous differential expression analysis
anals <- load_diff(gse_names, data_dir)
# run meta-analysis
es <- es_meta(anals)
#get dprimes
dprimes <- get_dprimes(es)
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