andrewrech/antigen.garnish: Ensemble Neoepitope Prediction from DNA Variants in R
Version 0.0.6

An R package for neoepitope analysis that takes human or murine DNA missense mutations, insertions, deletions, and gene fusions and performs ensemble neoepitope prediction using 7 algorithms. Input is a VCF file or table of peptides. Output is ranked neoepitopes and a summary of neoepitope load and fitness by sample. Neoepitopes are ranked by MHC I/II binding affinity, clonality, RNA expression, dissimilarity to the normal peptidome, and similarity to known immunogenic antigens.

Getting started

Package details

Maintainer
LicenseGPL-3
Version0.0.6
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("devtools")
library(devtools)
install_github("andrewrech/antigen.garnish")
andrewrech/antigen.garnish documentation built on June 21, 2018, 11:08 a.m.