lexi: LEXI: lncRNA expression imputation

Description Usage Arguments Value Examples

Description

Function to impute lncRNA expression profile from protein coding expression dataset

Usage

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lexi(train_pcg, train_lnc, my_pcg, gene_index, num = 100)

Arguments

train_pcg

training protein coding dataset. a numeric matrix with with row names indicating samples, and column names indicating protein coding gene IDs.

train_lnc

training lncRNA expression dataset. a numeric matrix with row names indicating samples, and column names indicating lncRNA IDs

my_pcg

test protein coding expression dataset. a numberic matrix with row names indicating samples, and column names indicating protein coding gene IDs.

gene_index

either gene name (character) or index (column number) of lncRNA to be imputed.

num

number of informative protein coding genes to be used in constructing imputation model. Default is 100 genes.

Value

a numeric vector containing imputed & standardized expression levels of the lncRNA

Examples

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lexi(train_pcg, train_lnc, my_pcg, gene_index="ENSG00000228630", num=100)
lexi(train_pcg, train_lnc, my_pcg, gene_index=25, num=100)

aritronath/LEXI documentation built on May 10, 2019, 1:27 p.m.