gpf_fraction_bound: Compute the bound fraction from the grand partition function

In benjbuch/summerrband: Analyse Gel-shift Assays

Description

Compute the bound fraction from the grand partition function

Usage

gpf_fraction_bound(x, binding_constants, type = "macro")

Arguments

x	A vector of ligand concentrations.
binding_constants	The values of the association equilibrium constant given as a (named) vector. See Details.
type	Either "micro" or "macro" (default).

Details

If type == "macro", the binding isotherm is computed for a macroscopic process using gpf_macro. The entries are assumed to be in ascending order, i.e., binding_constants[2] gives the apparent thermodynamic binding constant for associating the second ligand.

If type == "micro" the vector must contain the (named) microsocopic binding constants compatible with gpf_micro. Note that in this case, the entries are assumed to be in combinatorically increasing order, i.e., "a", "b", "c", "ab", "ac", "bc", "abc", for a third degree polynom. The entries can be named, but the names are not used for the assignment due to the complexity of the problem.

In either case, the degree is determined from the length of the binding constants vector.

benjbuch/summerrband documentation built on Dec. 19, 2021, 8:43 a.m.