fluorouracil: Pharmacokinetics of fluorouracil

In billdenney/PKdata: Pharmacokinetic Data Sets

Pharmacokinetics of fluorouracil

Description

Observed data set of concentration-time data for fluorouracil.

Usage

fluorouracil_conc

fluorouracil_dose

fluorouracil_demog

Format

fluorouracil_conc is a data frame describing concentration by time with the following variables:

ID

Subject identifier

TIME

Time (in minutes)

TIMEU

Units for time, "minutes"

NDOSE

Nominal dose (in mg/kg)

NDOSEU

Units for nominal dose, "mg/kg"

CONC

Plasma concentration of fluorouracil (in ug/mL)

CONCU

Units for plasma concentration of fluorouracil, "ug/mL"

fluorouracil_dose is a data frame describing dosing with the following variables:

ID

Subject identifier

NDOSE

Nominal dose (in mg/kg)

NDOSEU

Units for nominal dose, "mg/kg"

TIME

Time for start of dose (in minutes)

TIME_END

Time for end of dose (in minutes)

TIMEU

Units for time, "minutes"

ROUTE

Route of administration, "intravenous bolus"

An object of class data.frame with 48 rows and 7 columns.

An object of class data.frame with 8 rows and 7 columns.

An object of class data.frame with 8 rows and 17 columns.

References

MacMillan, William E., William H. Wolberg, and Peter G. Welling. 1978. "Pharmacokinetics of Fluorouracil in Humans." Cancer Research 38 (10): 3479-82.

billdenney/PKdata documentation built on Feb. 23, 2023, 12:01 p.m.