auc_integrate: Support function for AUC integration

In billdenney/pknca: Perform Pharmacokinetic Non-Compartmental Analysis

Support function for AUC integration

Description

Support function for AUC integration

Usage

auc_integrate(
  conc,
  time,
  clast,
  tlast,
  lambda.z,
  interval_method,
  fun_linear,
  fun_log,
  fun_inf
)

Arguments

conc	Measured concentrations
time	Time of the measurement of the concentrations
clast	The last concentration above the limit of quantification
tlast	Time of last concentration above the limit of quantification (will be calculated, if not provided)
lambda.z	The elimination rate (in units of inverse time) for extrapolation
interval_method	The method for integrating each interval of conc
fun_linear	The function to use for integration of the linear part of the curve (not required for AUC or AUMC functions)
fun_log	The function to use for integration of the logarithmic part of the curve (if log integration is used; not required for AUC or AUMC functions)
fun_inf	The function to use for extrapolation from the final measurement to infinite time (not required for AUC or AUMC functions.

billdenney/pknca documentation built on April 1, 2024, 10:45 p.m.