Description Usage Arguments Value References
In the three stage design under consideration, the groups are nested with assumed prevalences and fixed total sample size at each stage. This function returns the sample size for a specified group at a given stage, where the futility stage for the overall group test may be specified along with the chosen subgroup.
1 2 | groupSampleSize(prevalence, N, stage, group, HJFutileAtStage = NA,
chosenGroup = NA)
|
prevalence |
the vector of prevalence, will be normalized if not already so. The length of this vector implicitly indicates the number of groups J. |
N |
an integer vector of length 3 indicating total sample size at each of the three stages |
stage |
the stage of the trial |
group |
the group whose sample size is desired |
HJFutileAtStage |
is the stage at which overall futility
occured. Default |
chosenGroup |
the selected group if HJFutilityAtStage is not
|
the sample size for group
Adaptive Choice of Patient Subgroup for Comparing Two Treatments by Tze Leung Lai and Philip W. Lavori and Olivia Yueh-Wen Liao. Contemporary Clinical Trials, Vol. 39, No. 2, pp 191-200 (2014). http://www.sciencedirect.com/science/article/pii/S1551714414001311
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