data-onycholysisL: Data From The toenail onycholysis Study (Long Format)

In bozenne/repeated: Repeated Measurement Models for Discrete Times

Data From The toenail onycholysis Study (Long Format)

Description

Data from the toenail onychomycosis study, a randomized double-blind comparative study comparing Terbinafine (250 mg/day) against Itraconazole (200 mg/day) over 7 weeks. This dataset is in the long format (i.e. one line per measurement).

• id: patient identifier.

• group: treatment arm to which the patient has been randomized ("itraconazole" or "terbinafine").

• treatment: treatment recieved by the patient at a given timepoint ("none", "itraconazole", or "terbinafine").

• visit: index of time at which the measurement was taken (1 to 7).

• time: scheduled time, in months, for each measurement (0, 4, 8, 12, 24, 36, 48).

• obstime: time, in months, at which the measurement was taken (numeric between 0 and 18.5).

• response: degree of onycholysis (separation of the nail plate from the nail-bed). Can be 0 for none or mild, 1 for moderate or severe.

Usage

data(onycholysisL)

References

De Backer et al. Twelve weeks of continuous oral therapy for toenail onychomycosis caused by dermatophytes: A double-blind comparative trial of terbinafine 250 mg/day versus itraconazole 200 mg/day, Journal of the American Academy of Dermatology, (2020) 110. doi: 10.1016/s0190-9622(98)70486-4

bozenne/repeated documentation built on July 16, 2025, 11:16 p.m.