run_thunder: THUNDER estimates cell type proportions in bulk Hi-C datasets

Description Usage Arguments

View source: R/thunder.R

Description

THUNDER estimates cell type proportions in bulk Hi-C datasets

Usage

1
run_thunder(path_to_mixture, n_cell_types, itter = 200, out_init_nmf = NULL)

Arguments

path_to_mixture

String. Path to .tsv file of bulk Hi-C samples.

n_cell_types

Integer. The number of columns in the basis matrix of the deconvolution. Corresponds to the number of cell types in bulk Hi-C mixture.

itter

Integer. Number of itterations for NMF algorithm. Default is 200.

out_init_nmf

String. Default is NULL. If character, then saves the initial NMF fit as a .RDS object to specified file path.


brycerowland/thundeR documentation built on Dec. 14, 2021, 4:59 p.m.