chongma1989/tiltmod: Exponential Tilting Method for Reproducible Screening of Large Scale Testing Problem

Develop an exponential tilting method by conditioning on the false discovery rate to tilt a two component mixture of Beta distributions, yielding an tilted mixture model. Use a Boosted EM algorithm to fit a two-component mixture of Beta distributions for p-values or left tail areas of test statistics. The Boosted EM algorithm for the mixture model fitting is built in C++, which is quite fast and stable. The package also includes two utility functions to generate tilted false discovery rates and frequency network.

Getting started

Package details

AuthorChong Ma
MaintainerChong Ma <[email protected]>
LicenseGPL (>= 2)
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
chongma1989/tiltmod documentation built on Aug. 15, 2018, 3:33 a.m.