align.ABF.1: align.ABF.1

In cnfoley/hyprcoloc: Hypothesis Prioritisation in multi-trait Colocalization (HyPrColoc)

Description

align.ABF.1

Usage

align.ABF.1(
  Z,
  W,
  trait.cor,
  sample.overlap,
  ld.matrix,
  epsilon,
  reg.res,
  align.thresh,
  prior.1,
  prior.2,
  cor.adj.priors,
  uniform.priors,
  Zsq,
  Wsq,
  ind.traits
)

Arguments

Z	matrix of Z-scores
W	ratio matrix of prior standard deviation and observed standard errors
trait.cor	correlation matrix between traits
sample.overlap	matrix of sample overlap between traits
ld.matrix	LD matrix
epsilon	tolerance parameter
reg.res	regional result
align.thresh	alignment probability threshold
prior.1	prior probability of a SNP being associated with one trait
prior.2	1 - prior probability of a SNP being associated with an additional trait given that the SNP is associated with at least 1 other trait
cor.adj.priors	correlation adjusted priors
uniform.priors	uniform priors
Zsq	matrix of Z-scores squared
Wsq	matrix of W squared
ind.traits	are the traits independent or to be treated as independent

cnfoley/hyprcoloc documentation built on Feb. 15, 2021, 7:55 p.m.