lymphoma.prognosis: Lymphoma prognosis

In dave-harrington/eventtimedata: Event time data for teaching

Description

Data here was the training set in the derivation of the International Prognostic Index for non-Hodgkins lymphoma publised in Shipp et al, 1993

Usage

data("lymphoma.prognosis")

Format

A data frame with 1385 observations on the following 29 variables.

GENDER

Numeric; 1 = male, 2 = female

STAGE

Numeric; 1 - 4 with larger values denoting more widespread disease

B

Numeric; measure of extended disease within a stage. Stage 2B is worse than 2 but not as bad as 3. 1 = no, 2 = yes

PERF

Numeric; ECOG performance status. Larger values indicate poorer general health for patient

XTRA

Numeric; number of extra nodal sites of disease. 0 = none, 1 = 1 site, 2 = two or more sites.

BM

Numeric; presence of disease in the bone marrow. 1 = no, 2 = yes

LUNG

Numeric; presence of disease in the lung. 1 = no, 2 = yes.

CNS

Numeric; presence of disease in the central nervous system (CNS). 1 = no, 2 = yes.

LIVER

Numeric; presence of disease in the liver. 1 = no, 2 = yes.

GI

Numeric; presence of disease in the GI tract. 1 = no, 2 = yes.

SPLENIC

Numeric; presence of disease in the spleen. 1 = no, 2 = yes.

LDH_1

Numeric; value of LDH (lactose dehydrogenase) reported for the patient. Measured in units/liter (U/L).

LDH_2

Numeric; lab normal value of LDH (lactose dehydrogenase) reported for hospital where the patient was treated. Measured in units/liter (U/L).

ALBUM_1

Numeric; albumin level reported for the patient. Measured in grams/deciliter (g/dl).

ALBUM_2

Numeric; lab normal for albumin level for the hospital treating the patient. Measured in grams/deciliter (g/dl).

SURVIVAL

Numeric; status of survival. 1 = alive, 2 = dead, 3 = lost to follow-up.

AGE

Numeric; measured in years

LDHRATIO

Numeric; ratio of measured LDH to lab normal. More reliable than LDH itself because of possible variation in units of measurement.

AGE60

Numeric; Indicator for age > 60. 1 = no, 2 = yes

STAGE4

Numeric; Indicator for stage 4 disease. 1 = no, 2 = yes

BULK

Numeric; presence of bulky disease. 1 = no, 2 = yes

PS

Numeric; Binary indicator for performance status. 1 = performance status 0 or 1, 2 = 3 or 4

LDHX1NL

Numeric; binary indicator for ldh ratio greater that 1 times normal. 1 = no; 2 = yes.

LDHX15NL

Numeric; binary indicator for ldh ratio greater that 1.5 times normal. 1 = no; 2 = yes.

LDHX2NL

Numeric; binary indicator for ldh ratio greater that 2 times normal. 1 = no; 2 = yes.

LDHX3NL

Numeric; binary indicator for ldh ratio greater that 3 times normal. 1 = no; 2 = yes.

ALBRATIO

Numeric; ratio of measured albumin to lab normal. More reliable than albumin itself because of possible variation in units of measurement.

ALBX1NL

Numeric; binary indicator for albumin ratio greater that 1 times normal. 1 = no; 2 = yes.

SURVTIME

Numeric; survival time in years

Source

Data used in Shipp MA, Harrington DP, et al. for The International Non-Hodgkin's Lymphoma Prognostic Factors Project. A predictive model for aggressive non-Hodgkin's lymphoma. N Engl J Med 1993; 329:987-94.

References

Provided by D Harrington

Examples

data(lymphoma.prognosis)
table(lymphoma.prognosis$STAGE)
stage.factor = as.factor(lymphoma.prognosis$STAGE)
died = lymphoma.prognosis$SURVIVAL - 1
died[died == 2] = 0 #recoding the lost to follow-up to censored
survival.time = lymphoma.prognosis$SURVTIME
lymphoma.survival <- survfit(Surv(survival.time, died) ~ stage.factor)
lymphoma.survival

dave-harrington/eventtimedata documentation built on May 7, 2020, 2 p.m.