The PeCorA package detects quantitative disagreements between peptides mapped to the same protein. It initially format the output of proteomics processing tools such as MaxQuant into an adecuate format for the PeCorA algorithm. This algorithm fits linear models to assess whether the slope of a peptide’s change across treatment groups differs from the slope of all other peptides assigned to the same protein. Finally, visualization tools are provided to explore resulting discordant peptides, including boxplots.
|Bioconductor views||DataImport MassSpectrometry Proteomics|
|Package repository||View on GitHub|
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