PeCorA_preprocessing: PeCorA_preprocessing
In demar01/PeCorA: Peptide correlation analysis

Description Usage Arguments Details Value Author(s) Examples

steps to pre-process data for PeCorA

PeCorA_preprocessing(
  pecora_format,
  area_column_name,
  threshold_to_filter,
  control_name
)

`pecora_format`	dataframe in PeCorA format
`area_column_name`	numeric column number with peak areas
`threshold_to_filter`	numeric threshold for peak areas to filter
`control_name`	character control reference

Peak areas are log transformed and scaled to center. After global scaling, each peptide scaling was performed to center each peptide relative to the mean of the control group’s peak area.

dataframe output of pre-processed data ready for PeCorA analysis

Maria Dermit maria.dermit@qmul.ac.uk

if(interactive()){
scaled_peptides <- PeCorA_preprocessing(pecora_format,
                                         area_column_name=4,
                                         threshold_to_filter=100,
                                         control_name="control")
}