hic_scale: Perform library scaling on a hicexp object

In dozmorovlab/multHiCcompare: Normalize and detect differences between Hi-C datasets when replicates of each experimental condition are available

Perform library scaling on a hicexp object

Description

Perform library scaling on a hicexp object

Usage

hic_scale(hicexp)

Arguments

hicexp

A hicexp object.

Details

This function will perform library scaling on a hicexp object. Scaling is performed separately for each chromosome. This is an alternative normalization method to the cyclic loess and fastlo methods also provided in multiHiCcompare. Use this normalization method if for some reason you do not want to remove trends in the data and only want to normalize based on library size.

Value

A hicexp object.

Examples

data("hicexp2")
hicexp2 <- hic_scale(hicexp2)

dozmorovlab/multHiCcompare documentation built on April 30, 2022, 3:02 p.m.