R/PANACEA.R

In egeulgen/PANACEA: Personalized Network-Based Anti-Cancer Therapy Evaluation

#' PANACEA: Personalized Network-based Anti-Cancer Therapy Evaluation
#'
#' Identification of the most appropriate pharmacotherapy for each patient based
#' on genomic alterations is a major challenge in personalized oncology.
#' \code{PANACEA} is a collection of personalized anti-cancer drug prioritization
#' approaches utilizing network methods. The methods utilize personalized
#' "driverness" scores from 'driveR' to rank drugs, mapping these onto a
#' protein-protein interaction network (PIN). The "distance-based" method scores
#' each drug based on these scores and distances between drugs and genes to rank
#' given drugs. The "RWR" method propagates these scores via a random-walk with
#' restart framework to rank the drugs.
#'
#' @seealso \code{\link{score_drugs}} for the wrapper function for scoring of
#' drugs via network-based methods
#'
#' @name PANACEA
"_PACKAGE"