make_der: Makes a dose effect relationship function for a specified...

In eghuang/synergy: Tools for Synergy/Antagonism Modeling

Description

Outputs a dose effect relationship (DER) for a single ion with parameters dose and LET. The ion may be a low-LET or HZE ion and non-targeted effects may be specified.

Usage

make_der(data, HZE, NTE = TRUE, phi = 2000, y_0 = 0.046404)

Arguments

data	Data.frame of single ion data.
HZE	Boolean for presence of HZE ions
NTE	Boolean for presence of non-targeted effects
phi	Numeric constant
y_0	Numeric constant corresponding to background effect

Details

data must have a numeric column "dose" and a numeric weight column "NWeight". If a paper uses dose in Gy care is needed in preceding and following lines to rescale from cGy.

Value

Function

Author(s)

Edward Greg Huang <[e-mail]>

Examples

ion_data <- load_ion_data("one_ion.csv")

LLET_der    <- make_der(ion_data, FALSE)
HZE_nte_der <- make_der(ion_data, TRUE, TRUE)
HZE_te_der  <- make_der(ion_data, TRUE, FALSE)

eghuang/synergy documentation built on Dec. 31, 2019, 8:55 a.m.