Antagonism Modeling

Description Usage Arguments Details Value Author(s) Examples

Outputs a dose effect relationship (DER) model for a single ion with parameters dose and LET. The ion may be a low-LET or HZE ion and non-targeted effects may be specified.

1	make_model(data, HZE, NTE = TRUE, phi = 2000, y_0 = 0.046404)

`data`	Data.frame of single ion data.
`HZE`	Boolean for presence of HZE ions
`NTE`	Boolean for presence of non-targeted effects
`phi`	Numeric constant
`y_0`	Numeric constant corresponding to background effect

data must have a numeric column "dose" and a numeric weight column "NWeight".

nls model

Edward Greg Huang <eghuang@berkeley.edu>

ion_data <- load_ion_data("one_ion.csv")

LLET_model    <- make_model(ion_data, FALSE)
HZE_nte_model <- make_model(ion_data, TRUE, TRUE)
HZE_te_model  <- make_model(ion_data, TRUE, FALSE)