Description Usage Arguments Examples
This function interpolates the QTL location error for an experimental mapping population with replicates based on dense simulated power results in simulations with only a single observation per strain.
1 2 3 | interpolate.qtl.distance(r1.results, qtl.effect.sizes,
strain.effect.sizes = 0, num.replicates, n.alleles, n.strains,
n.mean.pseudo = 10)
|
r1.results |
Data frame of power estimates from simulations based on a single observation per strain. r1.dist.dat is included in SPARCC for this purpose. |
qtl.effect.sizes |
The desired QTL effect sizes for which power estimates will be interpolated from dense single observation results. |
strain.effect.sizes |
DEFAULT: 0. The desired proportions of variance due to background strain effect for hypothetical population in which power is evaluated. |
num.replicates |
The desired number of replicates for a hypothetical study in which to evaluate power. |
n.alleles |
The number of functional alleles for the simulated QTL. |
n.strains |
The number of CC strains for the desired interpolated power estimate. |
n.mean.psuedo |
DEFAULT: 10. The number of psuedo observations (of 2.5) to be used for regularization. |
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