PrecisionTrialDrawer-package | R Documentation |
PrecisionTrialDrawer is a package that a allows the design and study of a cancer panel to create pilot sets for a clinical trial.
It allows simulations on real TCGA data to design a possible clinical trial, both as basket or umbrella design.
Furthermore, it can provide an easy function to calculate genomic space occupied by the cancer panel in a commonly used bed format ready to be submitted to a NGS company.
Giorgio Melloni, Alessandro Guida
Cbioportal web site MD Anderson TCGA Fusion Portal
# Retrieve a Cancer Panel data(cpObj) # Show the number of covered samples coveragePlot(cpObj , alterationType=c("mutations" , "copynumber") , grouping=c("group" , "tumor_type"))
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