Provides a general framework for clinical trial simulations based on the Clinical Scenario Evaluation (CSE) approach. The package supports a broad class of data models (including clinical trials with continuous, binary, survival-type and count-type endpoints as well as multivariate outcomes that are based on combinations of different endpoints), analysis strategies and commonly used evaluation criteria.
Package details | 
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| Author | Gautier Paux, Alex Dmitrienko. | 
| Maintainer | Gautier Paux <gautier@paux.fr> | 
| License | GPL-2 | 
| Version | 1.0.9 | 
| URL | http://gpaux.github.io/Mediana/ | 
| Package repository | View on GitHub | 
| Installation | 
                Install the latest version of this package by entering the following in R:
                
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