GenerateReport: Clinical Scenario Evaluation Report

In gpaux/Mediana: Clinical Trial Simulations

Description

This function generates a Word-based report to present a detailed description of the simulation parameters (data, analysis and evaluation models) and results.

Usage

GenerateReport(
  presentation.model = NULL,
  cse.results,
  report.filename,
  report.template = NULL
)

Arguments

presentation.model	defines a PresentationModel object.
cse.results	defines a CSE object returned by the CSE function.
report.filename	defines the output filename of the word-based document generated.
report.template	defines a word-based template (optional).

Details

This function requires the package officer. A customized template can be specified in the argument report.template (optional), which consists in a Word document to place in the working directory folder.

References

http://gpaux.github.io/Mediana/

See Also

See Also CSE and PresentationModel.

Examples

## Not run: 
# Outcome parameter set 1
outcome1.placebo = parameters(mean = 0, sd = 70)
outcome1.treatment = parameters(mean = 40, sd = 70)

# Outcome parameter set 2
outcome2.placebo = parameters(mean = 0, sd = 70)
outcome2.treatment = parameters(mean = 50, sd = 70)

# Data model
case.study1.data.model = DataModel() +
  OutcomeDist(outcome.dist = "NormalDist") +
  SampleSize(c(50, 55, 60, 65, 70)) +
  Sample(id = "Placebo",
         outcome.par = parameters(outcome1.placebo, outcome2.placebo)) +
  Sample(id = "Treatment",
         outcome.par = parameters(outcome1.treatment, outcome2.treatment))


# Analysis model
case.study1.analysis.model = AnalysisModel() +
  Test(id = "Placebo vs treatment",
       samples = samples("Placebo", "Treatment"),
       method = "TTest")

# Evaluation model
case.study1.evaluation.model = EvaluationModel() +
  Criterion(id = "Marginal power",
            method = "MarginalPower",
            tests = tests("Placebo vs treatment"),
            labels = c("Placebo vs treatment"),
            par = parameters(alpha = 0.025))

# Simulation Parameters
case.study1.sim.parameters = SimParameters(n.sims = 1000, proc.load = 2, seed = 42938001)

# Perform clinical scenario evaluation
case.study1.results = CSE(case.study1.data.model,
                          case.study1.analysis.model,
                          case.study1.evaluation.model,
                          case.study1.sim.parameters)


# Reporting
case.study1.presentation.model = PresentationModel() +
  Section(by = "outcome.parameter") +
  Table(by = "sample.size") +
  CustomLabel(param = "sample.size",
              label= paste0("N = ",c(50, 55, 60, 65, 70))) +
  CustomLabel(param = "outcome.parameter",
              label=c("Standard 1", "Standard 2"))

# Report Generation
GenerateReport(presentation.model = case.study1.presentation.model,
               cse.results = case.study1.results,
               report.filename = "Case study 1 (normally distributed endpoint).docx")


## End(Not run)

gpaux/Mediana documentation built on May 31, 2021, 1:22 a.m.