joineR-package: joineR: Joint Modelling of Repeated Measurements and...
In graemeleehickey/joineR: Joint Modelling of Repeated Measurements and Time-to-Event Data
joineR-package R Documentation
joineR: Joint Modelling of Repeated Measurements and Time-to-Event Data
Description
Analysis of repeated measurements and time-to-event data via random effects joint models. Fits the joint models proposed by Henderson and colleagues \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1093/biostatistics/1.4.465")} (single event time) and by Williamson and colleagues (2008) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1002/sim.3451")} (competing risks events time) to a single continuous repeated measure. The time-to-event data is modelled using a (cause-specific) Cox proportional hazards regression model with time-varying covariates. The longitudinal outcome is modelled using a linear mixed effects model. The association is captured by a latent Gaussian process. The model is estimated using am Expectation Maximization algorithm. Some plotting functions and the variogram are also included. This project is funded by the Medical Research Council (Grant numbers G0400615 and MR/M013227/1).
Author(s)
Maintainer: Graeme L. Hickey graemeleehickey@gmail.com (ORCID)
Authors:
Pete Philipson peter.philipson1@newcastle.ac.uk (ORCID)
Ines Sousa isousa@mct.uminho.pt (ORCID)
Peter J. Diggle p.diggle@lancaster.ac.uk (ORCID)
Paula Williamson p.r.williamson@liverpool.ac.uk (ORCID)
Ruwanthi Kolamunnage-Dona kdrr@liverpool.ac.uk (ORCID)
Robin Henderson robin.henderson@ncl.ac.uk
Other contributors:
Maria Sudell m.e.sudell@liverpool.ac.uk [contributor]
Medical Research Council (Grant numbers: G0400615 and MR/M013227/1) [funder]
See Also
Useful links:
graemeleehickey/joineR documentation built on Jan. 1, 2025, 12:55 p.m.
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| joineR-package | R Documentation |
joineR: Joint Modelling of Repeated Measurements and Time-to-Event Data
Description
Analysis of repeated measurements and time-to-event data via random effects joint models. Fits the joint models proposed by Henderson and colleagues \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1093/biostatistics/1.4.465")} (single event time) and by Williamson and colleagues (2008) \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1002/sim.3451")} (competing risks events time) to a single continuous repeated measure. The time-to-event data is modelled using a (cause-specific) Cox proportional hazards regression model with time-varying covariates. The longitudinal outcome is modelled using a linear mixed effects model. The association is captured by a latent Gaussian process. The model is estimated using am Expectation Maximization algorithm. Some plotting functions and the variogram are also included. This project is funded by the Medical Research Council (Grant numbers G0400615 and MR/M013227/1).
Author(s)
Maintainer: Graeme L. Hickey graemeleehickey@gmail.com (ORCID)
Authors:
Pete Philipson peter.philipson1@newcastle.ac.uk (ORCID)
Ines Sousa isousa@mct.uminho.pt (ORCID)
Peter J. Diggle p.diggle@lancaster.ac.uk (ORCID)
Paula Williamson p.r.williamson@liverpool.ac.uk (ORCID)
Ruwanthi Kolamunnage-Dona kdrr@liverpool.ac.uk (ORCID)
Robin Henderson robin.henderson@ncl.ac.uk
Other contributors:
Maria Sudell m.e.sudell@liverpool.ac.uk [contributor]
Medical Research Council (Grant numbers: G0400615 and MR/M013227/1) [funder]
See Also
Useful links:
R Package Documentation
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