subclonal.test: Subclonal test H0: mean_X1 + mean_X2 <= mean_X

Description Usage Arguments

Description

Return a list of p-value and confidence intervals of X-(X1+X2) if p-value is small, reject H0, otherwise, not enough evidence to reject H0

Usage

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subclonal.test(vaf.col.name, parent.cluster, sub.clusters = NULL,
  boot = NULL, cdf = NULL, min.cluster.vaf = 0, alpha = 0.05)

Arguments

boot:

output of generate.boot(), if NULL, test using VAFs

vaf.col.name:

name of the VAF column

parent.cluster:

the cluster of mutations representing the parent clone

sub.clusters:

vector of sub clusters to test if they can be all directly arise from the parent clone; if NULL, the parent.cluster will be tested against 0 (this will help determine if this (parent)clone represents with high enough cell frac to report)

cdf:

Clonal data frame with VAF


hadaxu/clonevol-mirror documentation built on May 17, 2019, 9:42 a.m.