infer.clonal.models.2: (Deprecated) This function does not work well for >=3 samples...
In hadaxu/clonevol-mirror: What the package does (one line)
Description
Infer clonal structures and evolution models for multi cancer
samples from a single patients (eg. primary tumors, metastatic tumors,
xenograft tumors, multi-region samples, etc.)
Usage
1
infer.clonal.models.2(c, model = "monoclonal")
Arguments
c:
clonality analysis data frame, consisting of N+1 columns. The first
column must be named 'cluster' and hold variant cluster number (ie. use number
to name cluster, starting from 1,2,3... 0 is reserved for normal cell clone).
The next N columns contain VAF estimated for the corresponding cluster
(values range from 0 to 0.5)
model:
cancer evolution model to use, c('monoclonal', 'polyclonal').
monoclonal model assumes the orginal tumor (eg. primary tumor) arises from
a single normal cell; polyclonal model assumes the original tumor can arise
from multiple cells (ie. multiple founding clones). In the polyclonal model,
the total VAF of the separate founding clones must not exceed 0.5
hadaxu/clonevol-mirror documentation built on May 17, 2019, 9:42 a.m.
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Description
Infer clonal structures and evolution models for multi cancer samples from a single patients (eg. primary tumors, metastatic tumors, xenograft tumors, multi-region samples, etc.)
Usage
1 | infer.clonal.models.2(c, model = "monoclonal")
|
Arguments
c: |
clonality analysis data frame, consisting of N+1 columns. The first column must be named 'cluster' and hold variant cluster number (ie. use number to name cluster, starting from 1,2,3... 0 is reserved for normal cell clone). The next N columns contain VAF estimated for the corresponding cluster (values range from 0 to 0.5) |
model: |
cancer evolution model to use, c('monoclonal', 'polyclonal'). monoclonal model assumes the orginal tumor (eg. primary tumor) arises from a single normal cell; polyclonal model assumes the original tumor can arise from multiple cells (ie. multiple founding clones). In the polyclonal model, the total VAF of the separate founding clones must not exceed 0.5 |
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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