README.md

In hadexversum/powerHDX: Efficient Simulation of HDX-MS Data and Tools for the Statistical Analysis

Power calculations for Hydrogen/Deuterium Exchange experiments

This R package implements methods for

• simulation of isotope distribution of deuterated peptides (theoretical spectra) based on the code provided by Zhong-Yuan Kan,
• creating deuteration curves based on theoretical spectra with multiple technical replicates and a given error structure,
• testing differential deuterium uptake,
• power calculations for Hydrogen/Deuterium Exchange experiments.

Development version can be downloaded from Github:

if (!require(devtools)) {
  install.packages('devtools')
}
devtools::install_github("hadexversum/powerHaDeX")

hadexversum/powerHDX documentation built on Aug. 31, 2022, 7:47 p.m.