to_list: Convert galgo.Obj to list

In harpomaxx/galgoR-package: An Evolutionary Framework for the Identification and Study of Prognostic Gene Expression Signatures in Cancer

Description

The current function transforms a galgo.Obj to a list

Usage

to_list(output)

Arguments

output

An object of class galgo.Obj

Value

The current function restructurates a galgo.Obj to a more easy to understand an use list. This output is particularly useful if one wants to select a given solution and use its outputs in a new classifier. The output of type list has a length equals to the number of solutions obtained by the galgo algorithm.

Basically this output is a list of lists, where each element of the output is named after the solution's name (solution.n, where n is the number assigned to that solution), and inside of it, it has all the constituents for that given solution with the following structure:

1. output$solution.n$Genes: A vector of the features included in the solution

2. output$solution.n$k: The number of partitions found in that solution

3. output$solution.n$SC.Fit: The average silhouette coefficient of the partitions found

4. output$solution.n$Surv.Fit: The survival fitness value

5. output$solution.n$Rank: The solution rank

6. CrowD: The solution crowding distance related to the rest of the solutions

Author(s)

Martin E Guerrero-Gimenez, [e-mail]

Examples

# load example dataset
library(breastCancerTRANSBIG)
data(transbig)
Train <- transbig
rm(transbig)

expression <- Biobase::exprs(Train)
clinical <- Biobase::pData(Train)
OS <- survival::Surv(time = clinical$t.rfs, event = clinical$e.rfs)

# We will use a reduced dataset for the example
expression <- expression[sample(1:nrow(expression), 100), ]

# Now we scale the expression matrix
expression <- t(scale(t(expression)))

# Run galgo
output <- GSgalgoR::galgo(generations = 5, population = 15, 
prob_matrix = expression, OS = OS)
outputDF <- to_dataframe(output)
outputList <- to_list(output)

harpomaxx/galgoR-package documentation built on Oct. 26, 2020, 7:05 a.m.