Efficient implementations for all the popular synergy scoring models for drug combinations, including HSA, Loewe, Bliss and ZIP and visualization of the synergy scores as either a two-dimensional or a three-dimensional interaction surface over the dose matrix.
If you have any problems in using SynergyFinder, please contace Liye He ([email protected])
Code released under the Mozilla Public License 2.0.
In case you use the package in your work, we do appreciate a cition to our publication:
He L, Kulesskiy E, Saarela J, Turunen L, Wennerberg K, Aittokallio T, et al. (2018) Methods for High-throughput Drug Combination Screening and Synergy Scoring. In: von Stechow L, editor. Cancer Systems Biology: Methods and Protocols. New York, NY: Springer New York. P351-98.
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