FastMS: Fast Molecular Signatures Analysis via clusterProfilter

Description Usage Arguments Details Author(s) See Also Examples

View source: R/BI_FastMS.R

Description

Fast Molecular Signatures Analysis via clusterProfilter

Usage

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FastMS(genes, geneList, default.universe = T, pAdjustMethod = "BH",
  pvalueCutoff = list(enrichMS = 0.05, gseMS = 0.05),
  qvalueCutoff = 0.1, verbose = TRUE,
  save.path = "Molecular Signatures", names = "love")

Arguments

genes

a character of genes.The ENSEMBL id is the best.Note that no replicate should exist.

geneList

a named numeric of genes.The ENSEMBL id is the best.Note that no replicate should exist.

default.universe

whether to use default universe.If default.universe = F,the background genes would be provide by geneList

pAdjustMethod

the mathod of pvalue adjustment

pvalueCutoff

a list of pvalue adjust method for enricher and GSEA

qvalueCutoff

cutoff of q value

verbose

LuckyVerbose gseplot running message or not

save.path

the sub path of saved files

names

the main path and part names of saved files

Details

More about MsigDB & GSEA: http://software.broadinstitute.org/gsea/msigdb/index.jsp

Author(s)

Weibin Huang<654751191@qq.com>

See Also

enricher; GSEA

Examples

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data(geneList, package = "DOSE")
genes = names(geneList)[1:100]
geneList = geneList
ms <- FastMS(genes,
             geneList,
             pAdjustMethod = "BH",
             pvalueCutoff = list(enrichMS=0.00001,
                                 gseMS = 0.00001),
             qvalueCutoff  = 0.2,
             cnet.showCategory = 5,
             verbose = TRUE,
             save.path = "Molecular Signatures",
             names = "love")

huangwb8/lucky documentation built on Oct. 16, 2019, 9:01 a.m.