PoolScreenExp-class: Class to store pooled CRISPR screening experiment

PoolScreenExp-classR Documentation

Class to store pooled CRISPR screening experiment

Description

The poolScreenExp class is an S4 class used to store sgRNA and gene related data as well as parameters necessary for statistical model.

Slots

sgRNAData

A SummarizedExperiment containing the data related to sgRNAs.

FittingIntervals

A vector defining the limits of the intervals used for fitting of null model.

LFCModelParameters

A vector of parameters estimated when fitting the null model.

GeneData

SummarizedExperiment containing the data related to genes.

FittingOptions

A named list with options for fitting: IntervalFraction - fraction of sgRNAs used in every fitting interval (default 0.1), alphaCutoff - alpha cutoff for alpha RRA algorithm (default: 0.05).


imkeller/gscreend documentation built on March 14, 2024, 9:09 a.m.