getInducedFreqs: Generate a cell state frequency distribution with induced...

In immunogenomics/scpost: Simulates single-cell datasets from input data

Description

Given a vector of cell state frequencies (log space), this function will induce a specified fold change (fc) into the specified cluster (clus)

Usage

getInducedFreqs(log_prior, clus, fc = 1, cf_sigma)

Arguments

log_prior	A named vector containing the mean frequencies of the prototype dataset's cell states (log space). The "estimateFreqVar" function returns this a mean frequency vector in linear space (can be transformed into log space via the "log" function).
clus	The name of the cluster in which a fold change will be induced.
fc	The magnitude of the fold change that will be induced in the chosen cluster. If no fold change is desired, set fc = 1.
cf_sigma	A matrix containing the covariance between cell states. This matrix is received as output from the "estimateFreqVar" function

Value

Returns a generated vector in which the designated cluster has the designated fold change induced

immunogenomics/scpost documentation built on July 28, 2021, 4:03 a.m.