R/IDOLOptimizedCpGs450klegacy.R

In immunomethylomics/FlowSorted.Blood.EPIC: Illumina EPIC data on immunomagnetic sorted peripheral adult blood cells

#'     IDOL Optimized CpGs for adult blood DNA methylation deconvolution EPIC
#'
#' @description
#'     This object is a vector of length 350 consisting of the names of the IDOL
#'     optimized CpGs to use in the older 450K platform.
#'     These CpGs are used as the backbone for deconvolution and were selected
#'     because their methylation signature differs across the six
#'     normal leukocyte subtypes.
#'
#'
#' @format An object of class "character" of length 350.
#'
#'         The format is:
#'         chr [1:350] "cg14232368" "cg15087459" "cg20538211" "cg11944101" ...
#'
#' @references LA Salas et al. (2018). \emph{An optimized library for
#' reference-based deconvolution of whole-blood biospecimens assayed using the
#' Illumina HumanMethylationEPIC BeadArray}. Genome Biology 19, 64. doi:
#' \href{https://dx.doi.org/10.1186/s13059-018-1448-7}{10.1186/s13059-018-1448-7}
#' @references DC Koestler et al. (2016). \emph{Improving cell mixture
#' deconvolution by identifying optimal DNA methylation libraries (IDOL)}.
#' BMC bioinformatics. 17, 120. doi:
#' \href{https://dx.doi.org/10.1186/s13059-018-1448-7}{10.1186/s13059-018-1448-7}.
#'
#' @examples
#' # data ("IDOLOptimizedCpGs450klegacy")
#' # head(IDOLOptimizedCpGs450klegacy)
#' # See ?estimateCellCounts2 for deconvolution examples
"IDOLOptimizedCpGs450klegacy"