Description Usage Arguments Value Author(s) References
The function is to calculate the SPU statistics
1 | spuval(U, V, gamma1, gamma2, K, weight = F)
|
U, |
the Score vector |
V, |
the variance-covariance matrix of U |
gamma1, |
power candidates |
gamma2, |
power candidates |
K, |
number of traits |
weight, |
TRUE or FALSE, default is FALSE |
the SPU statistics
Zhiyuan (Jason) Xu, Yiwei Zhang and Wei Pan
Wei Pan, Junghi Kim, Yiwei Zhang, Xiaotong Shen and Peng Wei (2014) A powerful and adaptive association test for rare variants, Genetics, 197(4), 1081-95
Yiwei Zhang, Zhiyuan Xu, Xiaotong Shen, Wei Pan (2014) Testing for association with multiple traits in generalized estimation equations, with application to neuroimaging data. Neuroimage. 96:309-25
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