SPU.mulT: The function for adaptive sum of powered score (aSPU) test

Description Usage Arguments Details Value Author(s) References

Description

It gives the simulation-based p-values of the sum of powered score (SPU) with different power and aSPU test.

Usage

1
SPU.mulT(U, V, pow = c(1:8, Inf), B)

Arguments

U,

Score vector

V,

variance-covariance matrix of U

pow,

the power vector for aSPU tests.

B,

number of simulations

Details

the suggested power term is c(1:8, Inf)

Value

simulation-based p-values of the sum of powered score (SPU) with different power and aSPU test

Author(s)

Zhiyuan (Jason) Xu, Yiwei Zhang and Wei Pan

References

Wei Pan, Junghi Kim, Yiwei Zhang, Xiaotong Shen and Peng Wei (2014) A powerful and adaptive association test for rare variants, Genetics, 197(4), 1081-95

Yiwei Zhang, Zhiyuan Xu, Xiaotong Shen, Wei Pan (2014) Testing for association with multiple traits in generalized estimation equations, with application to neuroimaging data. Neuroimage. 96:309-25


jasonzyx/APaSPU documentation built on May 18, 2019, 5:55 p.m.