Description Details Author(s) References See Also
It gives p-value of aSPU test based on approximated score vector. This test is applicable to both maximum-likelihood estimation and estimating function-based models.
The DESCRIPTION file:
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how to use the package approx_aSPU()
Zhiyuan (Jason) Xu and Wei Pan
Maintainer: Zhiyuan (Jason) Xu <xuxx0284@umn.edu>
Wei Pan, Junghi Kim, Yiwei Zhang, Xiaotong Shen and Peng Wei (2014) A powerful and adaptive association test for rare variants, Genetics, 197(4), 1081-95
Yiwei Zhang, Zhiyuan Xu, Xiaotong Shen, Wei Pan (2014) Testing for association with multiple traits in generalized estimation equations, with application to neuroimaging data. Neuroimage. 96:309-25
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