jchen1981/OrderShapeEM: Optimal false discovery rate control using auxiliary (order) information based on a shape-constrained EM algorithm
The package implements a scalable and tuning parameter-free FDR control procedure for large-scale multiple testing exploiting the auxiliary information that reflects the order of the prior null probability. Both the prior null probabilities and the alternative p-value distribution are estimated using isotonic regression (pool-adjacent-violators algorithm).
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Package details |
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| Author | Jun Chen, Xianyang Zhang, Hongyuan Cao |
| Maintainer | Jun Chen <chen.jun2@mayo.edu> |
| License | GPL-2 |
| Version | 1.0 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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