R Package for MR Framework GRAPPLE

calCor | Calculate the '(k + 1)' by '(k + 1)' correlation matrix... |

findLocalModes | findLocal maximum modes of a series of points |

findModes | Use the multiple modes of the robust profile likelihood... |

getInput | SNP selection and clumping based on GWAS summary statistics |

grappleRobustEst | Robust multivariate MR estimation |

harmonise_data | Harmonise the alleles and effects between the exposure and... |

harmonise_function | Harmonisation function |

rho.huber | Huber loss function and its derivatives |

rho.l2 | L2 loss function and its derivatives |

rho.tukey | Tukey's beweight loss function and its derivatives |

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