#' Disentangling direct from indirect relationships in association networks
#' @param pathname
#' @param filename
#' @param outputname
#' @return
#' @author Contact: Xu Liu \email{xliu@@issas.ac.cn}
#' @references
#' @export
#idirect
#The function of idirect addresses the three main problems of ill-conditioning, self-loop and interaction strength overflow that may exist in previous methods, e.g., Pearson and Spearman
#Note that since idirect is compiled from python, the function only provides support for py3.5 3.8 3.9, cited by Xiao et al., 2022.
idirect = function(pathname=NULL, filename = NULL, outputname = NULL){
os <- import("os")
os$chdir(pathname)
time =import("time")
idir =import("idirect")
nh =import("net_handler")
fh =import("file_handler")
t0 = time$time()
G = fh$read_file_weighted_edges(filename, t0)
S = idir$direct_association(G[[1]], t0=t0)
S2 = nh$merge(G[[1]], S[[1]])
St = fh$save_sorted_turple(S2, in_file=filename)
fh$save_file_weighted_edges(St, outputname, t0=t0)
}
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