Description Usage Arguments Value Examples
Calibrate a variant map from MaveDB to Bayes Factors
1 2 3 |
ssid |
the scoreset id (URN) from MaveDB |
ensembls |
a vector of ensembl IDs for the target gene |
symbols |
a vector of gene symbols of the target gene |
drawPlot |
boolean value indicating whether a plot of variant distributions
should be drawn. Defaults to |
minMaf |
the minimum Minor Allele Frequency required for variants to be considered benign |
flip |
logical; whether to apply the flip transformation to the scores |
homozygous |
logical; filter benign variants to only those occuring homozygously. |
overrideCache |
logical; whether to override local cache. |
logger |
a yogilogger object to which to write log messages. |
a data.frame
containing the original scores
input
with an additional column llr
, representing the log likelihood ratio
(i.e. log Bayes Factor)
1 2 3 4 | maveUrn <- "urn:mavedb:00000001-c-2"
ensembls <- c("ENSG00000198668","ENSG00000143933","ENSG00000160014")
symbols <- c("CALM1","CALM2","CALM3")
calmBFs <- map2bf.mavedb(maveUrn,ensembls,symbols)
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