find_complexes: Locate submatrices (protein complexes) on the diagonal of a...

Description Usage Arguments

View source: R/bowtie_functions.R

Description

Locate high-scoring square submatrices along the diagonal of a first-order direct interaction matrix.

Usage

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find_complexes(
  full_matrix,
  min_conf_score = 0.75,
  max_complex_size = 500,
  give_up_expand = 50
)

Arguments

full_matrix

A first-order direct interaction matrix containing scores between 0-1, where 1 indicates an interaction with highest confidence and 0 indicates no interaction.

min_conf_score

The minimum average score of a submatrix to be accepted as a protein complex (default: 0.75).

max_complex_size

The maximum size of a submatrix (default: 500).

give_up_expand

Give up expanding a submatrix for a given seed when exceeding N proteins in each direction (default: 50). This parameter was implemented to reduce computing time.


k-niss/bowtie documentation built on March 10, 2020, 10:10 a.m.