sim_4way_pedigree: Simulate pedigree for 4-way intercross

In kbroman/simcross: Simulate Experimental Crosses

Simulate pedigree for 4-way intercross

Description

Simulate a 4-way cross, among four inbred lines (a table of individual, mom, dad, sex)

Usage

sim_4way_pedigree(ngen = 1, nsibs = 100)

Arguments

ngen	Number of intercross generations (1 or 2)
nsibs	Vector with number of siblings in the sibships in the last generation.

Details

We start with a set of 4 individuals (representing four inbred lines), and make a pair of crosses to generate a pair of heterozygous individuals. These are then crosses to generate a set of F1 individuals. If ngen==1, we stop there, with sum(nsibs) individuals in this last generation. If gen==2, we generate length(nsibs) male/female pairs of F1 offspring; these are intercrossed to generate a set of sibships, with lengths defined by the values in nsibs. Individuals in the last generation are alternating female/male.

Value

A data frame with five columns: individual ID, mother ID, father ID, sex, and generation. Founders have 0 for mother and father ID. Sex is coded 0 for female and 1 for male.

See Also

sim_from_pedigree(), sim_ril_pedigree(), sim_do_pedigree(), sim_ail_pedigree()

Examples

# 100 F1s between heterozygous parents
tab <- sim_4way_pedigree(1, 100)
# could also do this
tab2 <- sim_4way_pedigree(1, rep(10, 10))

# 120 F2s in 10 sibships each of size 12
tab3 <- sim_4way_pedigree(ngen=2, rep(12, 10))

kbroman/simcross documentation built on Jan. 13, 2024, 10:31 p.m.