Description Usage Arguments Value Author(s)
function begins the online rPCA process. It is the wrapper that takes in GRanges and outputs GRanges with decomposition
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cov |
GRanges object containig the GC corrected cov data outputed from fragCounter. Needs metadata with header "reads.corrected". |
mc.cores |
interger (default == 1). Number of cores to use for parallelization. |
detergent.pon.path |
string. Path to pon/detergent genrated using normal samples. |
verbose |
boolean (default == TRUE). Outputs progress. |
whole_genome |
boolean (default = TRUE). For this function always set this parameter to TRUE. |
use.blacklist |
boolean (default = FALSE). Whether to exclude off-target markers in case of Exomes or targeted sequqnecing. If set to TRUE, needs a GRange marking if each marker is set to be excluded or not. |
chr |
integer (default == NA). Depricated. Can be used to decompose a single chromosome. |
germline.filter |
boolean (default == TRUE). If germline markers need to be removed from decomposition. |
germline.file |
character (default == NA). Path to file with germline markers. |
GRange object with decomposition
Aditya Deshpande
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