getPosteriorParams: getPosteriorParams

View source: R/classify.dd.R

getPosteriorParamsR Documentation

getPosteriorParams

Description

Given the observations for a single gene and its clustering information, return the calculated posterior parameters

Usage

getPosteriorParams(y, mcobj, alpha, m0, s0, a0, b0)

Arguments

y

Numeric data vector for one gene (log-transformed non-zeroes)

mcobj

Object returned by mclustRestricted

alpha

Value for the Dirichlet concentration parameter

m0

Prior mean value for generating distribution of cluster means

s0

Prior precision value for generating distribution of cluster means

a0

Prior shape parameter value for the generating distribution of cluster precision

b0

Prior scale parameter value for the generating distribution of cluster precision

Value

A list of posterior parameter values under the DP mixture model framework, given the data and prior parameter values.

References

Korthauer KD, Chu LF, Newton MA, Li Y, Thomson J, Stewart R, Kendziorski C. A statistical approach for identifying differential distributions in single-cell RNA-seq experiments. Genome Biology. 2016 Oct 25;17(1):222. https://genomebiology.biomedcentral.com/articles/10.1186/s13059-016-1077-y


kdkorthauer/scDD documentation built on March 27, 2022, 5:11 a.m.