tests/testthat/_snaps/independent-test-gsBoundSummary.md
In keaven/gsDesign: Group Sequential Design
Test gsBoundSummary for gsDesign Object
Analysis Value Efficacy
IA 1: 20% Z 3.2527
N/Fixed design N: 0.2 p (1-sided) 0.0006
~delta at bound 2.2179
P(Cross) if delta=0 0.0006
P(Cross) if delta=1 0.0370
IA 2: 40% Z 2.9860
N/Fixed design N: 0.41 p (1-sided) 0.0014
~delta at bound 1.4398
P(Cross) if delta=0 0.0018
P(Cross) if delta=1 0.1883
IA 3: 60% Z 2.6917
N/Fixed design N: 0.61 p (1-sided) 0.0036
~delta at bound 1.0597
P(Cross) if delta=0 0.0047
P(Cross) if delta=1 0.4530
IA 4: 80% Z 2.3737
N/Fixed design N: 0.82 p (1-sided) 0.0088
~delta at bound 0.8093
P(Cross) if delta=0 0.0110
P(Cross) if delta=1 0.7229
Final Z 2.0253
N/Fixed design N: 1.02 p (1-sided) 0.0214
~delta at bound 0.6176
P(Cross) if delta=0 0.0250
P(Cross) if delta=1 0.9000
Test gsBoundSummary for gsDesign Object with Nname set
Analysis Value Efficacy
IA 1: 20% Z 3.2527
samplesize: 0.2 p (1-sided) 0.0006
~delta at bound 2.2179
P(Cross) if delta=0 0.0006
P(Cross) if delta=1 0.0370
IA 2: 40% Z 2.9860
samplesize: 0.41 p (1-sided) 0.0014
~delta at bound 1.4398
P(Cross) if delta=0 0.0018
P(Cross) if delta=1 0.1883
IA 3: 60% Z 2.6917
samplesize: 0.61 p (1-sided) 0.0036
~delta at bound 1.0597
P(Cross) if delta=0 0.0047
P(Cross) if delta=1 0.4530
IA 4: 80% Z 2.3737
samplesize: 0.82 p (1-sided) 0.0088
~delta at bound 0.8093
P(Cross) if delta=0 0.0110
P(Cross) if delta=1 0.7229
Final Z 2.0253
samplesize: 1.02 p (1-sided) 0.0214
~delta at bound 0.6176
P(Cross) if delta=0 0.0250
P(Cross) if delta=1 0.9000
Test gsBoundSummary for gsSurv Object
Analysis Value Efficacy Futility
IA 1: 33% Z 3.0107 -0.2388
N: 460 p (1-sided) 0.0013 0.5944
Events: 33 ~HR at bound 0.3457 1.0879
Month: 1 P(Cross) if HR=1 0.0013 0.4056
P(Cross) if HR=0.5 0.1412 0.0148
IA 2: 67% Z 2.5465 0.9410
N: 460 p (1-sided) 0.0054 0.1733
Events: 65 ~HR at bound 0.5298 0.7907
Month: 1 P(Cross) if HR=1 0.0062 0.8347
P(Cross) if HR=0.5 0.5815 0.0437
Final Z 1.9992 1.9992
N: 460 p (1-sided) 0.0228 0.0228
Events: 97 ~HR at bound 0.6655 0.6655
Month: 2 P(Cross) if HR=1 0.0233 0.9767
P(Cross) if HR=0.5 0.9000 0.1000
Test gsBoundSummary for gsDesign Object, test.type > 1
Analysis Value Efficacy Futility
IA 1: 20% Z 3.2527 -0.9016
N/Fixed design N: 0.22 p (1-sided) 0.0006 0.8164
~HR at bound 0.0000 46.6290
P(Cross) if HR=0 0.0006 0.1836
P(Cross) if HR=1 0.0417 0.0077
IA 2: 40% Z 2.9860 -0.0367
N/Fixed design N: 0.44 p (1-sided) 0.0014 0.5147
~HR at bound 0.0001 1.1171
P(Cross) if HR=0 0.0018 0.5037
P(Cross) if HR=1 0.2096 0.0192
IA 3: 60% Z 2.6917 0.6945
N/Fixed design N: 0.66 p (1-sided) 0.0036 0.2437
~HR at bound 0.0013 0.1811
P(Cross) if HR=0 0.0047 0.7737
P(Cross) if HR=1 0.4902 0.0363
IA 4: 80% Z 2.3737 1.3603
N/Fixed design N: 0.88 p (1-sided) 0.0088 0.0869
~HR at bound 0.0064 0.0551
P(Cross) if HR=0 0.0109 0.9215
P(Cross) if HR=1 0.7556 0.0619
Final Z 2.0253 2.0253
N/Fixed design N: 1.1 p (1-sided) 0.0214 0.0214
~HR at bound 0.0211 0.0211
P(Cross) if HR=0 0.0226 0.9774
P(Cross) if HR=1 0.9000 0.1000
Test gsBoundSummary for gsDesign Object, when nFixSurv is set
Analysis Value Efficacy Futility
IA 1: 20% Z 3.2527 -0.9016
N/Fixed design N: 0.22 p (1-sided) 0.0006 0.8164
~RR at bound 0.0000 95.5538
P(Cross) if RR=0 0.0006 0.1836
P(Cross) if RR=1 0.0417 0.0077
IA 2: 40% Z 2.9860 -0.0367
N/Fixed design N: 0.44 p (1-sided) 0.0014 0.5147
~RR at bound 0.0000 1.1404
P(Cross) if RR=0 0.0018 0.5037
P(Cross) if RR=1 0.2096 0.0192
IA 3: 60% Z 2.6917 0.6945
N/Fixed design N: 0.66 p (1-sided) 0.0036 0.2437
~RR at bound 0.0004 0.1316
P(Cross) if RR=0 0.0047 0.7737
P(Cross) if RR=1 0.4902 0.0363
IA 4: 80% Z 2.3737 1.3603
N/Fixed design N: 0.88 p (1-sided) 0.0088 0.0869
~RR at bound 0.0025 0.0321
P(Cross) if RR=0 0.0109 0.9215
P(Cross) if RR=1 0.7556 0.0619
Final Z 2.0253 2.0253
N/Fixed design N: 1.1 p (1-sided) 0.0214 0.0214
~RR at bound 0.0102 0.0102
P(Cross) if RR=0 0.0226 0.9774
P(Cross) if RR=1 0.9000 0.1000
Test with Probability Of Success(POS) set to TRUE
Analysis Value Efficacy Futility
IA 1: 33% Z 3.0107 -0.2387
Information: 41.64 p (1-sided) 0.0013 0.5943
Trial POS: 48.6% ~delta at bound 0.4666 -0.0370
Post IA POS: 56% P(Cross) if delta=0 0.0013 0.4057
P(Cross) if delta=0.3 0.1412 0.0148
IA 2: 67% Z 2.5465 0.9411
Information: 83.27 p (1-sided) 0.0054 0.1733
Post IA POS: 56.1% ~delta at bound 0.2791 0.1031
P(Cross) if delta=0 0.0062 0.8347
P(Cross) if delta=0.3 0.5815 0.0437
Final Z 1.9992 1.9992
Information: 124.91 p (1-sided) 0.0228 0.0228
~delta at bound 0.1789 0.1789
P(Cross) if delta=0 0.0233 0.9767
P(Cross) if delta=0.3 0.9000 0.1000
Test gsBoundSummary with "Spending" in exclude"
Analysis Value Efficacy Futility
IA 1: 50% Z 2.7500 0.4122
N: 168 p (1-sided) 0.0030 0.3401
~delta at bound -0.8143 -0.1221
B-value 1.9445 0.2915
CP 0.9965 0.0240
CP H1 0.9890 0.4805
PP 0.9710 0.0816
P(Cross) if delta=0 0.0030 0.6599
P(Cross) if delta=-0.69 0.3412 0.0269
Final Z 1.9811 1.9811
N: 336 p (1-sided) 0.0238 0.0238
~delta at bound -0.4148 -0.4148
B-value 1.9811 1.9811
P(Cross) if delta=0 0.0239 0.9761
P(Cross) if delta=-0.69 0.9000 0.1000
keaven/gsDesign documentation built on April 10, 2024, 6:21 a.m.
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Test gsBoundSummary for gsDesign Object
Analysis Value Efficacy
IA 1: 20% Z 3.2527
N/Fixed design N: 0.2 p (1-sided) 0.0006
~delta at bound 2.2179
P(Cross) if delta=0 0.0006
P(Cross) if delta=1 0.0370
IA 2: 40% Z 2.9860
N/Fixed design N: 0.41 p (1-sided) 0.0014
~delta at bound 1.4398
P(Cross) if delta=0 0.0018
P(Cross) if delta=1 0.1883
IA 3: 60% Z 2.6917
N/Fixed design N: 0.61 p (1-sided) 0.0036
~delta at bound 1.0597
P(Cross) if delta=0 0.0047
P(Cross) if delta=1 0.4530
IA 4: 80% Z 2.3737
N/Fixed design N: 0.82 p (1-sided) 0.0088
~delta at bound 0.8093
P(Cross) if delta=0 0.0110
P(Cross) if delta=1 0.7229
Final Z 2.0253
N/Fixed design N: 1.02 p (1-sided) 0.0214
~delta at bound 0.6176
P(Cross) if delta=0 0.0250
P(Cross) if delta=1 0.9000
Test gsBoundSummary for gsDesign Object with Nname set
Analysis Value Efficacy
IA 1: 20% Z 3.2527
samplesize: 0.2 p (1-sided) 0.0006
~delta at bound 2.2179
P(Cross) if delta=0 0.0006
P(Cross) if delta=1 0.0370
IA 2: 40% Z 2.9860
samplesize: 0.41 p (1-sided) 0.0014
~delta at bound 1.4398
P(Cross) if delta=0 0.0018
P(Cross) if delta=1 0.1883
IA 3: 60% Z 2.6917
samplesize: 0.61 p (1-sided) 0.0036
~delta at bound 1.0597
P(Cross) if delta=0 0.0047
P(Cross) if delta=1 0.4530
IA 4: 80% Z 2.3737
samplesize: 0.82 p (1-sided) 0.0088
~delta at bound 0.8093
P(Cross) if delta=0 0.0110
P(Cross) if delta=1 0.7229
Final Z 2.0253
samplesize: 1.02 p (1-sided) 0.0214
~delta at bound 0.6176
P(Cross) if delta=0 0.0250
P(Cross) if delta=1 0.9000
Test gsBoundSummary for gsSurv Object
Analysis Value Efficacy Futility
IA 1: 33% Z 3.0107 -0.2388
N: 460 p (1-sided) 0.0013 0.5944
Events: 33 ~HR at bound 0.3457 1.0879
Month: 1 P(Cross) if HR=1 0.0013 0.4056
P(Cross) if HR=0.5 0.1412 0.0148
IA 2: 67% Z 2.5465 0.9410
N: 460 p (1-sided) 0.0054 0.1733
Events: 65 ~HR at bound 0.5298 0.7907
Month: 1 P(Cross) if HR=1 0.0062 0.8347
P(Cross) if HR=0.5 0.5815 0.0437
Final Z 1.9992 1.9992
N: 460 p (1-sided) 0.0228 0.0228
Events: 97 ~HR at bound 0.6655 0.6655
Month: 2 P(Cross) if HR=1 0.0233 0.9767
P(Cross) if HR=0.5 0.9000 0.1000
Test gsBoundSummary for gsDesign Object, test.type > 1
Analysis Value Efficacy Futility
IA 1: 20% Z 3.2527 -0.9016
N/Fixed design N: 0.22 p (1-sided) 0.0006 0.8164
~HR at bound 0.0000 46.6290
P(Cross) if HR=0 0.0006 0.1836
P(Cross) if HR=1 0.0417 0.0077
IA 2: 40% Z 2.9860 -0.0367
N/Fixed design N: 0.44 p (1-sided) 0.0014 0.5147
~HR at bound 0.0001 1.1171
P(Cross) if HR=0 0.0018 0.5037
P(Cross) if HR=1 0.2096 0.0192
IA 3: 60% Z 2.6917 0.6945
N/Fixed design N: 0.66 p (1-sided) 0.0036 0.2437
~HR at bound 0.0013 0.1811
P(Cross) if HR=0 0.0047 0.7737
P(Cross) if HR=1 0.4902 0.0363
IA 4: 80% Z 2.3737 1.3603
N/Fixed design N: 0.88 p (1-sided) 0.0088 0.0869
~HR at bound 0.0064 0.0551
P(Cross) if HR=0 0.0109 0.9215
P(Cross) if HR=1 0.7556 0.0619
Final Z 2.0253 2.0253
N/Fixed design N: 1.1 p (1-sided) 0.0214 0.0214
~HR at bound 0.0211 0.0211
P(Cross) if HR=0 0.0226 0.9774
P(Cross) if HR=1 0.9000 0.1000
Test gsBoundSummary for gsDesign Object, when nFixSurv is set
Analysis Value Efficacy Futility
IA 1: 20% Z 3.2527 -0.9016
N/Fixed design N: 0.22 p (1-sided) 0.0006 0.8164
~RR at bound 0.0000 95.5538
P(Cross) if RR=0 0.0006 0.1836
P(Cross) if RR=1 0.0417 0.0077
IA 2: 40% Z 2.9860 -0.0367
N/Fixed design N: 0.44 p (1-sided) 0.0014 0.5147
~RR at bound 0.0000 1.1404
P(Cross) if RR=0 0.0018 0.5037
P(Cross) if RR=1 0.2096 0.0192
IA 3: 60% Z 2.6917 0.6945
N/Fixed design N: 0.66 p (1-sided) 0.0036 0.2437
~RR at bound 0.0004 0.1316
P(Cross) if RR=0 0.0047 0.7737
P(Cross) if RR=1 0.4902 0.0363
IA 4: 80% Z 2.3737 1.3603
N/Fixed design N: 0.88 p (1-sided) 0.0088 0.0869
~RR at bound 0.0025 0.0321
P(Cross) if RR=0 0.0109 0.9215
P(Cross) if RR=1 0.7556 0.0619
Final Z 2.0253 2.0253
N/Fixed design N: 1.1 p (1-sided) 0.0214 0.0214
~RR at bound 0.0102 0.0102
P(Cross) if RR=0 0.0226 0.9774
P(Cross) if RR=1 0.9000 0.1000
Test with Probability Of Success(POS) set to TRUE
Analysis Value Efficacy Futility
IA 1: 33% Z 3.0107 -0.2387
Information: 41.64 p (1-sided) 0.0013 0.5943
Trial POS: 48.6% ~delta at bound 0.4666 -0.0370
Post IA POS: 56% P(Cross) if delta=0 0.0013 0.4057
P(Cross) if delta=0.3 0.1412 0.0148
IA 2: 67% Z 2.5465 0.9411
Information: 83.27 p (1-sided) 0.0054 0.1733
Post IA POS: 56.1% ~delta at bound 0.2791 0.1031
P(Cross) if delta=0 0.0062 0.8347
P(Cross) if delta=0.3 0.5815 0.0437
Final Z 1.9992 1.9992
Information: 124.91 p (1-sided) 0.0228 0.0228
~delta at bound 0.1789 0.1789
P(Cross) if delta=0 0.0233 0.9767
P(Cross) if delta=0.3 0.9000 0.1000
Test gsBoundSummary with "Spending" in exclude"
Analysis Value Efficacy Futility
IA 1: 50% Z 2.7500 0.4122
N: 168 p (1-sided) 0.0030 0.3401
~delta at bound -0.8143 -0.1221
B-value 1.9445 0.2915
CP 0.9965 0.0240
CP H1 0.9890 0.4805
PP 0.9710 0.0816
P(Cross) if delta=0 0.0030 0.6599
P(Cross) if delta=-0.69 0.3412 0.0269
Final Z 1.9811 1.9811
N: 336 p (1-sided) 0.0238 0.0238
~delta at bound -0.4148 -0.4148
B-value 1.9811 1.9811
P(Cross) if delta=0 0.0239 0.9761
P(Cross) if delta=-0.69 0.9000 0.1000
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