Analysis Value Efficacy Futility
IA 1: 20% Z 3.2527 -0.9016
N/Fixed design N: 0.22 p (1-sided) 0.0006 0.8164
~RR at bound 8.4830 0.5529
P(Cross) if RR=0 0.0006 0.1836
P(Cross) if RR=1 0.0417 0.0077
IA 2: 40% Z 2.9860 -0.0367
N/Fixed design N: 0.44 p (1-sided) 0.0014 0.5147
~RR at bound 4.0065 0.9831
P(Cross) if RR=0 0.0018 0.5037
P(Cross) if RR=1 0.2096 0.0192
IA 3: 60% Z 2.6917 0.6945
N/Fixed design N: 0.66 p (1-sided) 0.0036 0.2437
~RR at bound 2.7774 1.3016
P(Cross) if RR=0 0.0047 0.7737
P(Cross) if RR=1 0.4902 0.0363
IA 4: 80% Z 2.3737 1.3603
N/Fixed design N: 0.88 p (1-sided) 0.0088 0.0869
~RR at bound 2.1818 1.5638
P(Cross) if RR=0 0.0109 0.9215
P(Cross) if RR=1 0.7556 0.0619
Final Z 2.0253 2.0253
N/Fixed design N: 1.1 p (1-sided) 0.0214 0.0214
~RR at bound 1.8137 1.8137
P(Cross) if RR=0 0.0226 0.9774
P(Cross) if RR=1 0.9000 0.1000
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