sim_trials: Simulates multiple trials
In labja/RollingSix: Rolling Six Design for Phase I Dose-Finding Trials

sim_trials

R Documentation

Simulates multiple trials

Simulates multiple trials

sim_trials(
  design,
  tox_rates,
  cohortsize = 1,
  start = 1,
  parallel_recruit = TRUE,
  futime,
  accrual,
  nsim,
  seed = 1
)

`design`	Thedose-finding design which is employed. Possible options are "RollingSix" for Rolling Six.
`tox_rates`	Vector of true toxicity rates for each dose level in ascending order
`cohortsize`	Number of patients in a cohort
`start`	Dose level to be used at the beginning of the trial
`parallel_recruit`	Whether recruitment is parallel or sequential. If FALSE recruitment is sequential i.e. recruitment is suspended until all DLT results are known
`futime`	Follow-up time in days
`accrual`	Expected number of patients to be recruited in a year
`nsim`	Number of simulated trials
`seed`	Seed for simulation