Description Usage Arguments Value
Settings for multiSOMe analysis
1 | modpar.new(modpar = NULL)
|
dataset.name |
all output will be stored in a folder with the name given |
meth.type |
type of Methylation Assay used. Either '27K' for Infinium HumanMethylation27K or 'K450' for Infinium HumanMethylation450K. If methylation data is already preprocessed and the data matrix contains methylation values per gene per sample set meth.type="" |
w |
weight used to either focus on gene expression (w=0), DNA methylation (w=1) or on both (w=0.5) |
mean.norm.exp |
enables centralization of the expression features (boolean) |
mean.norm.meth |
enables centralization of the methylation features (boolean) |
quant.exp |
enables quantile normalization of the expression samples (boolean) |
quant.meth |
enables quantile normalization of the expression samples (boolean) |
M |
enables calculation of M values out of methylation beta values (boolean) |
row.ids.exp |
type of rowname identifier in biomaRt database of gene expression matrix, for example 'ensembl_gene_id', "refseq_mrna" or 'external_gene_name'. For details see https://www.bioconductor.org/packages//2.7/bioc/vignettes/biomaRt/inst/doc/biomaRt.pdf |
row.ids.meth |
type of rowname identifier in biomaRt database of DNA methylation matrix, for example 'ensembl_gene_id', "refseq_mrna" or 'external_gene_name'. For details see https://www.bioconductor.org/packages//2.7/bioc/vignettes/biomaRt/inst/doc/biomaRt.pdf |
return.ids |
type of rowname identifier in biomaRt database to return, for example 'ensembl_gene_id' or 'external_gene_name'. For details see https://www.bioconductor.org/packages//2.7/bioc/vignettes/biomaRt/inst/doc/biomaRt.pdf |
modpar
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